CBC - Cannabichromene

Out of the big three cannabinoids (THC, CBD & CBC), Cannabichromene (CBC) rarely gets any attention beyond a mention. Unlike Tetrahydrocannabinol (THC), CBC does not share its psychoactive effects. 

SIDEBAR: You might see claims asserting that CBC is the second most concentrated cannabinoid in the plant after THC. My research indicates that assertion is based on only two studies and is not accurate. 

As described on the Cannabis Library page, cannabinoids interact with the CB1-R and CB2-R receptors, but they also interact with other receptors, too. CBC is known to interact with the TRPV1 receptor and other receptors as well. The research on CBC continues to indicate that it might modulate the effect of THC and other cannabinoids in important tways.

21      30      2     

In addition to the possible medical benefits listed below, there's also now a growing interest in CBC's potential to treat gastrointestinal and inflammatory disorders.

-anti-bacterial effects: Study 1; Study 2
-analgesic/pain relieving benefits: Study 1;Study 2

-may help inhibit depression: Study 1

​-CBC may increase the viability of developing brain cells, a process known as neurogenesis. Study 1

-might be neuroprotective, but may have opposite effect too: Study 1

-may stimulate bone growth, though I've not yet found a study to support this anecdotal claim

C        H       O

Cannabichromene (CBC) is ultimately formed when its precursor acid form, Cannabichrome Carboxylic Acid (CBCa), is converted to its neutral form - CBC. CBCa is one of the three major cannabinoid branches formed by Cannabigerolic Acid (CBGa). The cannabis plant possesses natural enzymes, referred to as "synthases", that break the CBGa down and convert it to one of the major cannabinoids. As shown in this graphic, we see how CBC is formed via decarboxylation of CBCa. 

About CBC

NOTES: Categorized as a "Major" cannabinoid in cannabis. CBC shares the same molecular formula as THC and CBD

Possible Therapeutic Effects